SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05262

Signal sequence   MRLLASVLLALFAVSHA

Length  17

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P23438,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05262.cif

Structure  SPKB05262.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1812.24684

Aliphatic index  172.3529412

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  659.96

Aromaticity  0.058823529

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -3.01333

Hydropathy 



Literature Information


Title  SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

DOI  NA,

Publication Year  1991

PubMed ID  1918067,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.