SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05258

Signal sequence   MKKIMLIASAMSALSLPFSASA

Length  22

Organism  Orientia tsutsugamushi (Rickettsia tsutsugamushi)

UniProt ID  P22940,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05258.cif

Structure  SPKB05258.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2268.81654

Aliphatic index  111.3636364

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  818.82

Aromaticity  0.045454545

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  33

X logP energy  -6.8632

Hydropathy 



Literature Information


Title  Purification and partial characterization of a type-specific antigen of Rickettsia tsutsugamushi.

DOI  10.1128/iai.57.5.1427-1431.1989,

Publication Year  1989

PubMed ID  2496028,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.