SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05257

Signal sequence   MKTIICLFTIAIAAMA

Length  16

Organism  Bombyx mori (Silk moth)

UniProt ID  P22922,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05257.cif

Structure  SPKB05257.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1711.21234

Aliphatic index  146.875

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  566.3

Aromaticity  0.0625

Average rotatable bonds  3.5

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  -1.4503

Hydropathy 



Literature Information


Title  Amino acid sequence of silkworm (Bombyx mori) hemolymph antitrypsin deduced from its cDNA nucleotide sequence: confirmation of its homology with serpins.

DOI  10.1093/oxfordjournals.jbchem.a123208,

Publication Year  1990

PubMed ID  2277028,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.