SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05251

Signal sequence   MPSAISRGLLLLAGLCYLVFGIMA

Length  24

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P22323,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05251.cif

Structure  SPKB05251.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2510.15234

Aliphatic index  154.5833333

Isoelectric point  8.527213491

Charge (pH=7)   0.935155858

Topological polar surface area  846.42

Aromaticity  0.083333333

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -3.09153

Hydropathy 



Literature Information


Title  Molecular cloning and sequence analysis of cDNAs coding for guinea pig alpha 1-antiproteinases S and F and contrapsin.

DOI  NA,

Publication Year  1991

PubMed ID  1985973,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.