SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05250

Signal sequence   MALKLLTLIALTCAAANA

Length  18

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  P22297,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05250.cif

Structure  SPKB05250.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26394

Aliphatic index  163.3333333

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  667.59

Aromaticity  0

Average rotatable bonds  3.277777778

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -4.5152

Hydropathy 



Literature Information


Title  Isolation and molecular cloning of transferrin from the tobacco hornworm, Manduca sexta. Sequence similarity to the vertebrate transferrins.

DOI  NA,

Publication Year  1990

PubMed ID  2254322,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.