SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05249

Signal sequence   MSSAMRKTTNSPVVRRLTAAAVALGSCLALAGPAGSAGA

Length  39

Organism  Streptomyces scabiei

UniProt ID  P22266,

Motif  1..39



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05249.cif

Structure  SPKB05249.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3716.35034

Aliphatic index  87.94871795

Isoelectric point  12.22275045

Charge (pH=7)   3.935704616

Topological polar surface area  1568.19

Aromaticity  0

Average rotatable bonds  3.051282051

Number of hydrogen bond donors  58

Number of hydrogen bond acceptors  56

X logP energy  -22.95579

Hydropathy 



Literature Information


Title  Cloning, sequencing, and regulation of expression of an extracellular esterase gene from the plant pathogen Streptomyces scabies.

DOI  10.1128/jb.172.12.7020-7026.1990,

Publication Year  1990

PubMed ID  2254271,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.