SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05247

Signal sequence   MSHRRMQLALSLVFILCGLFNSIFC

Length  25

Organism  Ovis aries (Sheep)

UniProt ID  P21814,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05247.cif

Structure  SPKB05247.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2900.57214

Aliphatic index  124.8

Isoelectric point  8.837902826

Charge (pH=7)   1.964937336

Topological polar surface area  1061.07

Aromaticity  0.12

Average rotatable bonds  3.84

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -6.63246

Hydropathy 



Literature Information


Title  The major progesterone-modulated proteins secreted into the sheep uterus are members of the serpin superfamily of serine protease inhibitors.

DOI  NA,

Publication Year  1989

PubMed ID  2464597,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.