SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05242

Signal sequence   MNMMTVKQQGVWAALLWPYLLTAS

Length  24

Organism  Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus)

UniProt ID  P20362,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05242.cif

Structure  SPKB05242.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2753.33094

Aliphatic index  101.6666667

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  991.62

Aromaticity  0.125

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -4.8127

Hydropathy 



Literature Information


Title  cDNA cloning of somatolactin, a pituitary protein related to growth hormone and prolactin.

DOI  10.1073/pnas.87.11.4330,

Publication Year  1990

PubMed ID  2349240,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.