SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05231

Signal sequence   MKATCWILAGFCLLFCCKA

Length  19

Organism  Gallus gallus (Chicken)

UniProt ID  P19204,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05231.cif

Structure  SPKB05231.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2122.70864

Aliphatic index  97.89473684

Isoelectric point  8.3409973

Charge (pH=7)   1.749495368

Topological polar surface area  675.18

Aromaticity  0.157894737

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -1.6793

Hydropathy 



Literature Information


Title  Calsequestrin, an intracellular calcium-binding protein of skeletal muscle sarcoplasmic reticulum, is homologous to aspartactin, a putative laminin-binding protein of the extracellular matrix.

DOI  10.1016/0006-291x(90)90895-t,

Publication Year  1990

PubMed ID  2302244,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.