SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05225

Signal sequence   MKLFYLLVICALSLAVMA

Length  18

Organism  Protophormia terraenovae (Northern blowfly) (Lucilia terraenovae)

UniProt ID  P18684,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05225.cif

Structure  SPKB05225.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1999.60214

Aliphatic index  178.8888889

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  624.5

Aromaticity  0.111111111

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  1.0365

Hydropathy 



Literature Information


Title  Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity.

DOI  10.1021/bi00022a012,

Publication Year  1995

PubMed ID  7779781,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.