SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05219

Signal sequence   MKTSIRYALLAAALTAATPALA

Length  22

Organism  Neisseria gonorrhoeae

UniProt ID  P17259,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05219.cif

Structure  SPKB05219.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2218.68304

Aliphatic index  125

Isoelectric point  10.45492462

Charge (pH=7)   1.99683554

Topological polar surface area  854.7

Aromaticity  0.045454545

Average rotatable bonds  3.136363636

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -7.29663

Hydropathy 



Literature Information


Title  Purification and characterization of the major iron-regulated protein expressed by pathogenic Neisseriae.

DOI  10.1084/jem.165.4.1041,

Publication Year  1987

PubMed ID  3559476,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.