SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05213

Signal sequence   MKSKNFKLSPSGRLAASLAIIFVSLNAYG

Length  29

Organism  Proteus mirabilis

UniProt ID  P16466,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05213.cif

Structure  SPKB05213.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3084.67014

Aliphatic index  104.4827586

Isoelectric point  11.13192842

Charge (pH=7)   3.996245472

Topological polar surface area  1216.85

Aromaticity  0.103448276

Average rotatable bonds  3.551724138

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  43

X logP energy  -11.69673

Hydropathy 



Literature Information


Title  Nucleotide sequencing of the Proteus mirabilis calcium-independent hemolysin genes (hpmA and hpmB) reveals sequence similarity with the Serratia marcescens hemolysin genes (shlA and shlB).

DOI  10.1128/jb.172.3.1206-1216.1990,

Publication Year  1990

PubMed ID  2407716,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.