SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05210

Signal sequence   MSRFSVLSFLILAIFLGGSIVKG

Length  23

Organism  Momordica charantia (Bitter gourd) (Balsam pear)

UniProt ID  P16094,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6LOQ,

Predicted Structure ID  SPKB05210.cif

Structure  SPKB05210.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2456.02754

Aliphatic index  148.2608696

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  872.36

Aromaticity  0.130434783

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -4.54463

Hydropathy 



Literature Information


Title  N-terminal sequence of some ribosome-inactivating proteins.

DOI  10.1111/j.1399-3011.1989.tb01280.x,

Publication Year  1989

PubMed ID  2753596,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.