SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05206

Signal sequence   MKKFLLVAVVGLAGITFA

Length  18

Organism  Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)

UniProt ID  P15452,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05206.cif

Structure  SPKB05206.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1878.38994

Aliphatic index  151.6666667

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  630.29

Aromaticity  0.111111111

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -1.0079

Hydropathy 



Literature Information


Title  Amino acid sequence of cytochrome c-552 from a thermophilic hydrogen-oxidizing bacterium, Hydrogenobacter thermophilus.

DOI  10.1128/jb.171.1.65-69.1989,

Publication Year  1989

PubMed ID  2536668,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.