SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05205

Signal sequence   MRVILLLLTLDVLGVSS

Length  17

Organism  Rattus norvegicus (Rat)

UniProt ID  P15399,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05205.cif

Structure  SPKB05205.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1842.31094

Aliphatic index  211.7647059

Isoelectric point  6.338718596

Charge (pH=7)   -0.001572528

Topological polar surface area  688.81

Aromaticity  0

Average rotatable bonds  3.647058824

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -3.06633

Hydropathy 



Literature Information


Title  Regulation of a bifunctional mRNA results in synthesis of secreted and nuclear probasin.

DOI  10.1073/pnas.86.20.7843,

Publication Year  1989

PubMed ID  2682630,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.