SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05196

Signal sequence   MKKTLLGSLILLAFAGNVQA

Length  20

Organism  Haemophilus influenzae

UniProt ID  P14212,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Fimbrium

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05196.cif

Structure  SPKB05196.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2088.57964

Aliphatic index  146.5

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  794.9

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -5.3676

Hydropathy 



Literature Information


Title  Cloning and expression in Escherichia coli of Haemophilus influenzae fimbrial genes establishes adherence to oropharyngeal epithelial cells.

DOI  10.1002/j.1460-2075.1989.tb08519.x,

Publication Year  1989

PubMed ID  2573518,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.