SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05184

Signal sequence   MAGKVTVAFFMFAMIAFLANFGYVEC

Length  26

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  P11919,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05184.cif

Structure  SPKB05184.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2879.50374

Aliphatic index  82.69230769

Isoelectric point  6.228791989

Charge (pH=7)   -0.063360742

Topological polar surface area  937.69

Aromaticity  0.230769231

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -2.4583

Hydropathy 



Literature Information


Title  Isolation and primary structure of the eclosion hormone of the tobacco hornworm, Manduca sexta.

DOI  10.1016/0006-291x(87)90592-4,

Publication Year  1987

PubMed ID  3304284,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.