SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05182

Signal sequence   MKVKKTYGFRKSKISKTLCGAVLGTVAAVSVAGQKVFA

Length  38

Organism  Streptococcus mutans

UniProt ID  P11657,

Motif  1..38



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05182.cif

Structure  SPKB05182.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3973.83804

Aliphatic index  89.73684211

Isoelectric point  11.20665696

Charge (pH=7)   7.933090621

Topological polar surface area  1568.76

Aromaticity  0.078947368

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  58

Number of hydrogen bond acceptors  57

X logP energy  -15.29703

Hydropathy 



Literature Information


Title  Molecular characterization of a surface protein antigen gene from serotype c Streptococcus mutans, implicated in dental caries.

DOI  10.1111/j.1365-2958.1989.tb00215.x,

Publication Year  1989

PubMed ID  2761390,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.