SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05171

Signal sequence   MKNKKMLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVK

Length  43

Organism  Bacillus cereus

UniProt ID  P10424,

Motif  1..43



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6W33,

Predicted Structure ID  SPKB05171.cif

Structure  SPKB05171.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4552.57474

Aliphatic index  104.1860465

Isoelectric point  10.67882183

Charge (pH=7)   4.937494592

Topological polar surface area  1792.91

Aromaticity  0.023255814

Average rotatable bonds  3.837209302

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  66

X logP energy  -16.4405

Hydropathy 



Literature Information


Title  Cloning and sequencing of the beta-lactamase I gene of Bacillus cereus 5/B and its expression in Bacillus subtilis.

DOI  10.1128/jb.163.2.487-492.1985,

Publication Year  1985

PubMed ID  2991192,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.