SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05170

Signal sequence   MARVLVLLSVVLVSLLVNQGRAS

Length  23

Organism  Cyprinus carpio (Common carp)

UniProt ID  P10298,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05170.cif

Structure  SPKB05170.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2438.01344

Aliphatic index  186.0869565

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  974.19

Aromaticity  0

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  32

X logP energy  -7.65486

Hydropathy 



Literature Information


Title  Purification of carp growth hormone and cloning of the complementary DNA.

DOI  10.1016/0167-4781(89)90045-6,

Publication Year  1989

PubMed ID  2920175,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.