SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05167

Signal sequence   MPKSLLLVLALALLAQTALA

Length  20

Organism  Doratifera vulnerans (Mottled cup moth)

UniProt ID  P0DUT4,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05167.cif

Structure  SPKB05167.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2050.61444

Aliphatic index  195.5

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  717

Aromaticity  0

Average rotatable bonds  3.35

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  -2.2393

Hydropathy 



Literature Information


Title  Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.

DOI  10.1073/pnas.2023815118,

Publication Year  2021

PubMed ID  33893140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.