SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05164

Signal sequence   MSKVILLCLIFALFACSIS

Length  19

Organism  Doratifera vulnerans (Mottled cup moth)

UniProt ID  P0DUS9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05164.cif

Structure  SPKB05164.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2072.65334

Aliphatic index  169.4736842

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  673.83

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -1.6528

Hydropathy 



Literature Information


Title  Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.

DOI  10.1073/pnas.2023815118,

Publication Year  2021

PubMed ID  33893140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.