SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05160

Signal sequence   MSKLLVLFVVSAMALLQFSMVEATP

Length  25

Organism  Doratifera vulnerans (Mottled cup moth)

UniProt ID  P0DUS4,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05160.cif

Structure  SPKB05160.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2726.38674

Aliphatic index  136.4

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  940.26

Aromaticity  0.08

Average rotatable bonds  3.56

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -4.1844

Hydropathy 



Literature Information


Title  Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.

DOI  10.1073/pnas.2023815118,

Publication Year  2021

PubMed ID  33893140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.