SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05158

Signal sequence   MKKTFLPIFLVILLASYALANP

Length  22

Organism  Doratifera vulnerans (Mottled cup moth)

UniProt ID  P0DUS2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05158.cif

Structure  SPKB05158.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2464.09054

Aliphatic index  150.9090909

Isoelectric point  10.24760792

Charge (pH=7)   1.996543817

Topological polar surface area  812.66

Aromaticity  0.136363636

Average rotatable bonds  3.5

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  30

X logP energy  -0.6768

Hydropathy 



Literature Information


Title  Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.

DOI  10.1073/pnas.2023815118,

Publication Year  2021

PubMed ID  33893140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.