SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05130

Signal sequence   MHFSGVAFILISMVLIGSIFETTVEA

Length  26

Organism  Tityus discrepans (Venezuelan scorpion)

UniProt ID  P0C1X6,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05130.cif

Structure  SPKB05130.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2813.36274

Aliphatic index  131.1538462

Isoelectric point  4.254269075

Charge (pH=7)   -1.907556364

Topological polar surface area  995.25

Aromaticity  0.115384615

Average rotatable bonds  3.5

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  37

X logP energy  -5.2663

Hydropathy 



Literature Information


Title  Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.

DOI  10.1002/pmic.200500525,

Publication Year  2006

PubMed ID  16705749,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.