SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05129

Signal sequence   MTMTRLKISKTLLAVMLTSAVATGSAYA

Length  28

Organism  Escherichia coli (strain K12)

UniProt ID  P0AFH8,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05129.cif

Structure  SPKB05129.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2930.57294

Aliphatic index  108.2142857

Isoelectric point  10.90180955

Charge (pH=7)   2.996540506

Topological polar surface area  1145.03

Aromaticity  0.035714286

Average rotatable bonds  3.5

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  44

X logP energy  -11.62893

Hydropathy 



Literature Information


Title  osmY, a new hyperosmotically inducible gene, encodes a periplasmic protein in Escherichia coli.

DOI  10.1128/jb.174.11.3637-3644.1992,

Publication Year  1992

PubMed ID  1317380,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.