General Information
SPKB ID SPKB05126
Signal sequence MRYIRLCIISLLATLPLAVHA
Length 21
Organism Escherichia coli
UniProt ID P0A9Z7,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 3D4F,
Predicted Structure ID SPKB05126.cif
Physicochemical Information
Molecular weight 2367.98294
Aliphatic index 176.6666667
Isoelectric point 9.501216221
Charge (pH=7) 2.026061638
Topological polar surface area 849.7
Aromaticity 0.047619048
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 30
X logP energy -2.81836
Hydropathy 
Literature Information
Title Single amino acid substitution between SHV-1 beta-lactamase and cefotaxime-hydrolyzing SHV-2 enzyme.
DOI 10.1016/0014-5793(88)80734-8,
Publication Year 1988
PubMed ID 3129309,
Patent ID NA,
