SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05124

Signal sequence   MKKLTVAALAVTTLLSGSAFA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P0A915,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05124.cif

Structure  SPKB05124.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2093.55304

Aliphatic index  125.7142857

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  798.51

Aromaticity  0.047619048

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -7.2976

Hydropathy 



Literature Information


Title  Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis.

DOI  10.1002/elps.1150190539,

Publication Year  1998

PubMed ID  9629924,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.