SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05122

Signal sequence   MVPISIIRNRVAKVAVGSAAVLGLAVGFQTPAVA

Length  34

Organism  Streptomyces carzinostaticus

UniProt ID  P0A3R9,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05122.cif

Structure  SPKB05122.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3377.09544

Aliphatic index  137.6470588

Isoelectric point  12.51647815

Charge (pH=7)   2.997682643

Topological polar surface area  1302.73

Aromaticity  0.029411765

Average rotatable bonds  3.147058824

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  44

X logP energy  -11.57726

Hydropathy 



Literature Information


Title  Two- and three-dimensional proton NMR studies of apo-neocarzinostatin.

DOI  10.1021/bi00245a009,

Publication Year  1991

PubMed ID  1831044,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.