SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05118

Signal sequence   MIRFLVLSLLILTLFLTTPAVEG

Length  23

Organism  Trichosanthes kirilowii (Chinese snake gourd) (Chinese cucumber)

UniProt ID  P09989,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05118.cif

Structure  SPKB05118.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2561.20474

Aliphatic index  182.173913

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  874.85

Aromaticity  0.086956522

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -1.55043

Hydropathy 



Literature Information


Title  Primary amino acid sequence of alpha-trichosanthin and molecular models for abrin A-chain and alpha-trichosanthin.

DOI  NA,

Publication Year  1990

PubMed ID  2341399,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.