SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05117

Signal sequence   MKLSLSQPCSFSGALLLLAVSNLLVWEKVTS

Length  31

Organism  Mus musculus (Mouse)

UniProt ID  P09586,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05117.cif

Structure  SPKB05117.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3336.00814

Aliphatic index  135.1612903

Isoelectric point  8.540504393

Charge (pH=7)   0.937194639

Topological polar surface area  1260.45

Aromaticity  0.064516129

Average rotatable bonds  3.548387097

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  46

X logP energy  -10.2956

Hydropathy 



Literature Information


Title  Identification of proliferin mRNA and protein in mouse placenta.

DOI  10.1073/pnas.82.13.4356,

Publication Year  1985

PubMed ID  3859868,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.