SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05112

Signal sequence   MAQRRTSGTNLFMTVLCVVAMCRA

Length  24

Organism  Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica)

UniProt ID  P09319,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05112.cif

Structure  SPKB05112.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2660.24264

Aliphatic index  81.25

Isoelectric point  10.51794918

Charge (pH=7)   2.874024934

Topological polar surface area  1085.42

Aromaticity  0.041666667

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  39

X logP energy  -12.27299

Hydropathy 



Literature Information


Title  Complete amino acid sequences of a pair of fish (tilapia) prolactins, tPRL177 and tPRL188.

DOI  NA,

Publication Year  1988

PubMed ID  3379064,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.