SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05111

Signal sequence   MRQRRISGSNLMMVLCVVAMCRA

Length  23

Organism  Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica)

UniProt ID  P09318,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05111.cif

Structure  SPKB05111.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2626.28964

Aliphatic index  97.39130435

Isoelectric point  12.02344377

Charge (pH=7)   3.874021622

Topological polar surface area  1077.76

Aromaticity  0

Average rotatable bonds  3.956521739

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  38

X logP energy  -11.10802

Hydropathy 



Literature Information


Title  Complete amino acid sequences of a pair of fish (tilapia) prolactins, tPRL177 and tPRL188.

DOI  NA,

Publication Year  1988

PubMed ID  3379064,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.