General Information
SPKB ID SPKB05090
Signal sequence MKFTVTFLLIICTLSAFC
Length 18
Organism Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
UniProt ID P06498,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05090.cif
Physicochemical Information
Molecular weight 2051.59124
Aliphatic index 130
Isoelectric point 8.229691165
Charge (pH=7) 0.873739834
Topological polar surface area 664.96
Aromaticity 0.166666667
Average rotatable bonds 3.611111111
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -1.8492
Hydropathy 
Literature Information
Title The adenovirus E3 14.5-kilodalton protein, which is required for down-regulation of the epidermal growth factor receptor and prevention of tumor necrosis factor cytolysis, is an integral membrane protein oriented with its C terminus in the cytoplasm.
DOI 10.1128/JVI.66.3.1665-1673.1992,
Publication Year 1992
PubMed ID 1531370,
Patent ID NA,
