SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05089

Signal sequence   MAPWTRLLPLLALLSLWIPAPTRA

Length  24

Organism  Felis catus (Cat) (Felis silvestris catus)

UniProt ID  P06306,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05089.cif

Structure  SPKB05089.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2701.35484

Aliphatic index  146.6666667

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  913.53

Aromaticity  0.083333333

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -1.49656

Hydropathy 



Literature Information


Title  Characterization of cat insulin.

DOI  10.1016/0003-9861(86)90528-x,

Publication Year  1986

PubMed ID  3518635,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.