SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05081

Signal sequence   MEKKLLGIAILFVTVVSVLA

Length  20

Organism  Limulus polyphemus (Atlantic horseshoe crab)

UniProt ID  P03998,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05081.cif

Structure  SPKB05081.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2144.72774

Aliphatic index  185

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  746.02

Aromaticity  0.05

Average rotatable bonds  3.65

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -1.327

Hydropathy 



Literature Information


Title  Amino acid sequence of the coagulogen from Limulus polyphemus hemocytes.

DOI  NA,

Publication Year  1984

PubMed ID  6378904,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.