SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05078

Signal sequence   MARENTNKHYWLRKLKKGTASVAVALSVLGAGLVVNTNEVSA

Length  42

Organism  Streptococcus pyogenes serotype M5

UniProt ID  P02977,

Motif  1..42



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05078.cif

Structure  SPKB05078.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4498.22674

Aliphatic index  102.1428571

Isoelectric point  10.84919329

Charge (pH=7)   4.090406464

Topological polar surface area  1917.34

Aromaticity  0.047619048

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  64

X logP energy  -20.76056

Hydropathy 



Literature Information


Title  The complete amino acid sequence of a biologically active 197-residue fragment of M protein isolated from type 5 group A streptococci.

DOI  NA,

Publication Year  1984

PubMed ID  6368549,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.