SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05075

Signal sequence   MDCHTKETLGVTQWRRSTMLTLSLLYAITPADG

Length  33

Organism  Trypanosoma brucei brucei

UniProt ID  P02896,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05075.cif

Structure  SPKB05075.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3710.29614

Aliphatic index  85.75757576

Isoelectric point  7.357204574

Charge (pH=7)   0.028434695

Topological polar surface area  1517.08

Aromaticity  0.060606061

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  54

X logP energy  -15.26796

Hydropathy 



Literature Information


Title  Complete amino acids sequence of a variant surface glycoprotein (VSG 117) from Trypanosoma brucei.

DOI  10.1016/0022-2836(82)90474-0,

Publication Year  1982

PubMed ID  7120400,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.