SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05073

Signal sequence   MSTIKLSLCLLIMLAVCCYEANA

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  P02782,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05073.cif

Structure  SPKB05073.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2504.13254

Aliphatic index  144.3478261

Isoelectric point  6.067194068

Charge (pH=7)   -0.187310174

Topological polar surface area  890.85

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -5.4192

Hydropathy 



Literature Information


Title  Prostate alpha-protein. Complete amino acid sequence of the component that inhibits nuclear retention of the androgen-receptor complex.

DOI  NA,

Publication Year  1982

PubMed ID  7198120,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.