SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05070

Signal sequence   MKLFTGLIFCSLVLGVSS

Length  18

Organism  Neovison vison (American mink) (Mustela vison)

UniProt ID  P02739,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05070.cif

Structure  SPKB05070.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1915.37964

Aliphatic index  140.5555556

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  664.96

Aromaticity  0.111111111

Average rotatable bonds  3.5

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -3.8998

Hydropathy 



Literature Information


Title  The primary structure of amyloid fibril protein AA in endotoxin-induced amyloidosis of the mink.

DOI  10.1111/j.1432-1033.1980.tb04441.x,

Publication Year  1980

PubMed ID  6767608,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.