SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05066

Signal sequence   MKFFIVLALCIVGAIA

Length  16

Organism  Chironomus thummi thummi (Midge)

UniProt ID  P02223,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05066.cif

Structure  SPKB05066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1709.22444

Aliphatic index  176.875

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  525.84

Aromaticity  0.125

Average rotatable bonds  3.4375

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  1.2012

Hydropathy 



Literature Information


Title  Hemoglobins, XXXVI: The primary structure of a dimeric insect hemoglobin (Erythrocruorin), component IX from Chironomus thummi thummi. Studies on the quarternary structure of the dimeric CTT-hemoglobins (author's transl)

DOI  10.1515/bchm2.1981.362.1.59,

Publication Year  1981

PubMed ID  7216162,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.