SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05063

Signal sequence   MHHTSMGIKMESQIQVFVFVFLWLSGVDG

Length  29

Organism  Mus musculus (Mouse)

UniProt ID  P01633,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05063.cif

Structure  SPKB05063.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3324.92124

Aliphatic index  93.79310345

Isoelectric point  6.499829359

Charge (pH=7)   -0.818270946

Topological polar surface area  1218.99

Aromaticity  0.137931034

Average rotatable bonds  3.75862069

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  44

X logP energy  -7.3245

Hydropathy 



Literature Information


Title  Sequence of the full-length immunoglobulin kappa-chain of mouse myeloma MPC 11.

DOI  10.1042/bj1710337,

Publication Year  1978

PubMed ID  418775,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.