SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05056

Signal sequence   MISMLRCTFFFLSVILITSYFVTPTMS

Length  27

Organism  Apis mellifera (Honeybee)

UniProt ID  P01499,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05056.cif

Structure  SPKB05056.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3149.87324

Aliphatic index  108.1481481

Isoelectric point  8.527213491

Charge (pH=7)   0.935155858

Topological polar surface area  1055.1

Aromaticity  0.185185185

Average rotatable bonds  3.62962963

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -5.03823

Hydropathy 



Literature Information


Title  Amino acid sequence of MCD-peptide, a specific mast cell-degranulating peptide from bee venom

DOI  NA,

Publication Year  1969

PubMed ID  5789872,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.