SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05053

Signal sequence   MKTLLLTLVVVTIVCLDLGYS

Length  21

Organism  Ophiophagus hannah (King cobra) (Naja hannah)

UniProt ID  P01412,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05053.cif

Structure  SPKB05053.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2294.87694

Aliphatic index  185.2380952

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.958

Hydropathy 



Literature Information


Title  Snake venoms. The amino-acid sequence of polypeptide DE-1 from Ophiophagus hannah (King cobra) venom.

DOI  10.1515/bchm2.1977.358.1.565,

Publication Year  1977

PubMed ID  881163,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.