SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05052

Signal sequence   MKTLLLTLVVVTIVCLDLGDS

Length  21

Organism  Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake)

UniProt ID  P01384,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05052.cif

Structure  SPKB05052.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2246.78954

Aliphatic index  185.2380952

Isoelectric point  4.10922374

Charge (pH=7)   -1.063392482

Topological polar surface area  826.86

Aromaticity  0

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -4.4316

Hydropathy 



Literature Information


Title  Amino acid sequence of a postsynaptic neurotoxin from the venom of the Australian tiger snake Notechis scutatus scutatus.

DOI  10.1016/s0300-9084(79)80172-8,

Publication Year  1979

PubMed ID  497256,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.