SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05045

Signal sequence   MVRKRALGLAGSALTLVLGAVGFTAPAQA

Length  29

Organism  Streptomyces nigrescens

UniProt ID  P01077,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05045.cif

Structure  SPKB05045.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2840.42334

Aliphatic index  121.3793103

Isoelectric point  12.51647815

Charge (pH=7)   2.997682643

Topological polar surface area  1122.93

Aromaticity  0.034482759

Average rotatable bonds  3.172413793

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -10.98696

Hydropathy 



Literature Information


Title  Amino acid sequence of Streptomyces metallo-proteinase inhibitor from Streptomyces nigrescens TK-23.

DOI  10.1093/oxfordjournals.jbchem.a135041,

Publication Year  1985

PubMed ID  3888972,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.