SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05024

Signal sequence   MKTLLLTLVVVTIVCLDLGYT

Length  21

Organism  Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix)

UniProt ID  O73856,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05024.cif

Structure  SPKB05024.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2308.90384

Aliphatic index  185.2380952

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.5695

Hydropathy 



Literature Information


Title  Six isoforms of cardiotoxin in malayan spitting cobra (Naja naja sputatrix) venom: cloning and characterization of cDNAs.

DOI  10.1016/s0304-4165(97)00143-8,

Publication Year  1998

PubMed ID  9565688,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.