SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05022

Signal sequence   MFSTGTLLLAALISPALA

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  O62644,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05022.cif

Structure  SPKB05022.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1790.19124

Aliphatic index  152.2222222

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  630.15

Aromaticity  0.055555556

Average rotatable bonds  3.055555556

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -4.1243

Hydropathy 



Literature Information


Title  A novel growth-promoting factor derived from fetal bovine cartilage, chondromodulin II. Purification and amino acid sequence.

DOI  10.1074/jbc.271.37.22657,

Publication Year  1996

PubMed ID  8798437,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.