SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05020

Signal sequence   MKSLHIICLLFIFVARGNS

Length  19

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  O57690,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05020.cif

Structure  SPKB05020.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2162.68244

Aliphatic index  143.6842105

Isoelectric point  9.834331048

Charge (pH=7)   2.026620329

Topological polar surface area  787.27

Aromaticity  0.105263158

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -3.90503

Hydropathy 



Literature Information


Title  Characterization and evolution of a gene encoding a Trimeresurus flavoviridis serum protein that inhibits basic phospholipase A2 isozymes in the snake's venom.

DOI  10.1111/j.1432-1033.1997.00838.x,

Publication Year  1997

PubMed ID  9395334,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.