SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05019

Signal sequence   MKIEKLGKSSVASSIALLLLSNTVDA

Length  26

Organism  Staphylococcus aureus

UniProt ID  O54082,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05019.cif

Structure  SPKB05019.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2689.20344

Aliphatic index  138.8461538

Isoelectric point  9.441546052

Charge (pH=7)   0.999320805

Topological polar surface area  1107.95

Aromaticity  0

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  40

X logP energy  -11.4586

Hydropathy 



Literature Information


Title  Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family.

DOI  10.1016/s0014-5793(98)01130-2,

Publication Year  1998

PubMed ID  9781679,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.